【Kowa】Colgen Kowa LX Tablets 18 tablets

First in Japan! This is a cold medicine containing loxoprofen sodium hydrate.
Effective against painful colds and fevers.

Efficacy/effect
Relief of cold symptoms (fever、 sore throat、 cough、 sputum、 chills、 headache、 runny nose、 stuffy nose、 sneezing、 joint pain、 muscle pain)

Usage/Dosage
Please take the following amount with water or warm water preferably within 30 minutes after a meal.
Age: Dose: Number of doses per day
Adults (15 years and older): 3 tablets: 3 times
Children under 15 years of age: Do not take
1. Please strictly follow the directions and dosage.
2. How to take out the tablet: As shown in the picture above、 firmly press the convex part of the PTP sheet containing the tablet with your fingertips、 tear the aluminum foil on the back、 take it out、 and take it. (If you accidentally swallow it whole、 it may pierce the esophageal mucosa or cause an unexpected accident.)

Ingredients/Amount
9 tablets in total
Loxoprofen sodium hydrate...204.3mg (180mg as anhydrous)
Dihydrocodeine phosphate...24mg
d-chlorpheniramine maleate...3.5mg
dl-methylephedrine hydrochloride...60mg
Guaifenesin...250mg
Anhydrous caffeine...40mg

Storage method
1. Avoid high temperatures and store in a cool、 dry place out of direct sunlight.
2. Please keep out of reach of children.
3. Do not transfer to another container. (It may cause misuse or change in quality.)
4. Please be careful when storing and carrying the PTP to avoid tearing the aluminum foil or damaging the tablets inside.
5. Do not take the product after the expiry date (written on the outer box).

Precautions for use
1. The following people should consult their doctor or pharmacist before taking the drug:
(1) Persons receiving treatment from a doctor or dentist.
(2) Pregnant women or people who appear to be pregnant.
(3) Elderly people.
(4) People who have had allergic symptoms due to medicines、 etc.
(5) People who have the following symptoms. High fever、 difficulty urinating
(6) Persons who have received the following diagnosis. Bronchial asthma、 ulcerative colitis、 Crohn's disease、 systemic lupus erythematosus、 mixed connective tissue disease、 thyroid dysfunction、 diabetes、 heart disease、 hypertension、 glaucoma、 respiratory dysfunction、 obstructive sleep apnea syndrome、 obesity
(7) Persons who have had the following diseases. Stomach/duodenal ulcer、 liver disease、 kidney disease、 blood disease
2. If the following symptoms appear after taking this medicine、 it may be a side effect、 so please stop taking it immediately and consult your doctor or pharmacist with this package insert.
(1) If symptoms such as an excessive drop in body temperature、 collapse (lack of strength)、 or cooling of the extremities (cold hands and feet) appear.
(2) If peptic ulcer or swelling appears. In addition、 in rare cases、 gastrointestinal bleeding (vomiting of blood、 nausea/vomiting、 abdominal pain、 black tar-like stools、 bloody stool、 etc.)、 gastrointestinal perforation (a hole in the digestive tract. Nausea、 vomiting、 severe abdominal pain、 etc.) Serious symptoms such as small intestine/large intestine stenosis/obstruction (nausea/vomiting、 abdominal pain、 abdominal distension、 etc.) may occur. In that case、 please see a doctor immediately.
(3) If the following symptoms appear.
Related parts...Symptoms
Skin: Rash、 redness、 itching
Digestive system: Nausea/vomiting、 loss of appetite、 heartburn、 abdominal pain、 stomatitis、 stomach discomfort、 abdominal distension、 indigestion
Neuropsychiatric system: dizziness、 headache、 numbness
Cardiovascular system: palpitations、 increased blood pressure
Urinary system: Difficulty urinating、 hematuria
Others: fever、 facial flush、 anemia、 fatigue、 chest pain
In rare cases、 the following serious symptoms may occur. In that case、 please see a doctor immediately.
Symptom name...Symptom
Shock (anaphylaxis): Immediately after taking the drug、 symptoms such as itchy skin、 hives、 hoarseness、 sneezing、 itchy throat、 difficulty breathing、 palpitations、 and clouded consciousness may occur.
Mucocutaneous oculomucocutaneous syndrome (Stevens-Johnson syndrome)、 toxic epidermal necrolysis、 erythema multiforme、 acute generalized exanthematous pustulosis...high fever、 redness of the eyes、 eye discharge、 sore lips、 sore throat、 Extensive skin rash/redness、 blisters appearing on red areas of the skin、 small bumps (pustules) appearing on reddened skin、 general malaise、 loss of appetite、 etc. that persist or worsen rapidly.
Liver dysfunction: Fever、 itching、 rash、 jaundice (yellowing of the skin and whites of the eyes)、 brown urine、 general malaise、 loss of appetite、 etc. may appear.
Kidney disorder: Fever、 rash、 decreased urine output、 general swelling、 general malaise、 joint pain (pain in the joints)、 diarrhea、 etc. may appear.
Aseptic meningitis: Severe headache accompanied by stiffness in the neck、 fever、 nausea、 and vomiting appear. (Such symptoms are particularly frequently reported in people receiving treatment for systemic lupus erythematosus or mixed connective tissue disease.)
Interstitial pneumonia: When you climb stairs or push yourself too hard、 you experience shortness of breath、 difficulty breathing、 dry cough、 fever、 etc.、 which appear suddenly or persist.
Rhabdomyolysis: Muscle pain in the limbs、 shoulders、 lower back、 etc.、 numbness in the limbs、 weakness、 stiffness、 general malaise、 reddish-brown urine、 etc.
Asthma: wheezing、 whistling、 and difficulty breathing when breathing.
Aplastic anemia: Bruises、 nosebleeds、 bleeding gums、 fever、 pale skin and mucous membranes、 fatigue、 palpitations、 shortness of breath、 feeling unwell and dizzy、 blood in the urine、 etc. appear.
Agranulocytosis: Sudden onset of high fever、 chills、 sore throat、 etc.
Blood disorders: sore throat、 fever、 general malaise、 whitish appearance on the face and behind the eyelids、 easy bleeding (bleeding gums、 nosebleeds、 etc.)、 bruising (color that does not disappear even when pressed)、 etc. appears.
Congestive heart failure: General malaise、 palpitations、 shortness of breath、 chest discomfort、 chest pain、 dizziness、 fainting、 etc. appear.
Respiratory depression: Shortness of breath、 difficulty breathing、 etc. appear.
3. The following symptoms may appear after taking this medicine. If these symptoms persist or worsen、 please stop taking this medicine and consult your doctor or pharmacist with this package insert.
dry mouth、 constipation、 diarrhea、 drowsiness
4. If your symptoms do not improve even after taking 5 to 6 times (especially if your fever continues for more than 3 days or if your fever recurs)、 stop taking the drug and bring this package insert to your doctor or pharmacist. Please consult